Pharmacy Information and Assistance Programs


EMD Serono Secured Distribution Program

Once you have a prescription from your healthcare provider, you can get Serostim® [somatropin (rDNA origin) for injection] through a network of pharmacies called the EMD Serono Secured Distribution Program. There are nearly 300 locations throughout the country, and you can also get your prescription through the network’s mail-order service.

The AXIS Center

EMD Serono, the company that provides Serostim®, has a group of support specialists at the AXIS Center. The AXIS Center offers trained Reimbursement Specialists who can assist you with verifying your insurance benefits, determining coverage options, and locating pharmacies in your area.

Patient Assistance Program

The Serostim® Patient Assistance Program (PAP) helps people who have HIV-associated wasting get the Serostim® treatment they need. Eligible patients must meet certain financial and medical criteria to receive Serostim® free of charge.

Copay Assistance Program

The Copay Assistance Program (CAP) can decrease or potentially eliminate out-of-pocket cost for eligible commercially- or privately-insured patients. Ask your healthcare provider for information on the Serostim® Copay Assistance Program.

  • Patients must have a prescription drug benefit that covers Serostim® and a valid Serostim® prescription
  • Patient can have multiple cards but is only allowed a max of 12 Serostim® prescription discounts per lifetime
  • Patients may not use card if patients receive drug benefits from Medicaid, a Medicare drug benefit plan, or other federal or state programs (includes state Medicaid assistance program and/or pharmaceutical patient assistance programs). Additionally, patients may not use card if their private insurance, HMO, or other health or pharmacy benefit program paid for the entire Serostim® prescription
  • Void in any state where prohibited by law, taxed, or otherwise restricted.
  • EMD Serono reserves the right to rescind, revoke or amend this offer at any time without notice

You can also call 1-877-714-AXIS (2947) to get more information about these programs.

Learn how to take Serostim

Important Risk Information and Indication Toggle Button

You Should not take Serostim® [somatropin (rDNA origin) for injection] if you have:

  • A critical illness due to complications after open heart surgery, abdominal surgery, serious injuries or have severe breathing problems
  • Cancer or undergoing treatment for cancer
  • Certain types of eye diseases caused by diabetes
  • Allergies to growth hormone or benzyl alcohol, an ingredient in the liquid used to mix Serostim®

What should I tell my healthcare provider before using Serostim®? Before using Serostim®, tell your doctor if you have or are:

  • A critical illness due to complications after open heart surgery, abdominal surgery or serious injuries or have severe breathing problems
  • Cancer or history of cancer
  • Skin lesions
  • Diabetes, a family history of diabetes or have been told by your doctor that you are at risk for diabetes
  • Multiple hormone deficiencies
  • Pregnant or nursing
  • Taking any medications, especially cyclosporine, hormone replacement therapy, insulin or other diabetes medications, drugs containing steroids, or drugs for seizure
  • Liver or kidney disease
  • Over 65 years of age
  • Have any other medical condition

What are the possible side effects of Serostim®? Serostim® may cause serious side effects including:

Concomitant Antiretroviral Therapy:
In some experimental systems, somatropin has been shown to increase HIV replication in vitro. Because of this possibility for acceleration of virus replication, it is recommended that you continue on your antiretroviral therapy for the duration of Serostim® treatment.

Impaired Glucose Tolerance/Diabetes:
Cases of new onset impaired glucose tolerance (pre-diabetes), new onset type 2 diabetes mellitus and worsening of current diabetes mellitus have been reported in patients receiving Serostim®. Some patients developed diabetic complications (ketoacidosis and diabetic coma). In some patients, these conditions improved when Serostim® was discontinued, while in others, the glucose intolerance persisted.

Intracranial Hypertension:
Intracranial hypertension, a rise in the pressure inside the skull, associated visual changes, headache, nausea, and/or vomiting has been reported.

Fluid Retention/Carpal Tunnel Syndrome:
Water retention may occur in adults during Serostim® therapy. Increased swelling, particularly in the hands and feet, muscle or joint pain may occur during treatment with Serostim®. Often these reactions resolve with analgesic therapy, or after decreasing the number of doses.
Carpal tunnel syndrome may occur during treatment with Serostim®. If the symptoms of carpal tunnel syndrome do not resolve by decreasing the weekly number of doses of Serostim®, it is recommended that treatment be discontinued.

Kaposi's sarcoma, Lymphoma and other Malignancies:
Kaposi's sarcoma (KS), lymphoma, and other malignancies are more common in HIV+ individuals. There was no increase in the incidence of Kaposi's sarcoma, lymphoma, or in the progression of cutaneous Kaposi's sarcoma in clinical studies of Serostim®. Patients with internal KS lesions were excluded from the studies. Potential effects on other malignancies are unknown.

Local and Systemic Reactions:
Injection sites should be changed (rotated) to avoid tissue atrophy. Patients should be informed that local and systemic reactions are possible and that prompt medical attention should be sought if allergic reactions occur.

Inflammation of the pancreas has been reported rarely in adults receiving growth hormone.

The most common side effects of Serostim® include:

  • In clinical trials the most common adverse reactions included swelling (particularly of the hands or feet), muscle pain, joint pain, numbness, and pain in extremities.
  • Injection site reactions (pain, numbness, redness, swelling). Change (rotate) your injection site to help lower your risk for injection site reactions.
  • Fluid retention
  • Bone, joint or muscle pain
  • Swelling of the extremities
  • Carpal tunnel syndrome
  • Breast enlargement
  • Nausea
  • Fatigue
  • Increase in blood glucose
  • Increase in triglycerides

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088. To report SUSPECTED ADVERSE REACTIONS, contact EMD Serono at 1-800-283-8088 ext. 5563.

This information is not intended to replace discussions with your doctor. For additional information about Serostim®, please consult the Prescribing Information and talk to your doctor.

Serostim® is available by prescription only.

Please see the full Prescribing Information for a complete discussion of Serostim®'s risks.


  1. 1. Moyle GJ, Daar ES, Gertner JM, et al. Growth hormone improves lean body mass, physical performance, and quality of life in subjects with HIV-associated weight loss or wasting on highly active antiretroviral therapy. J Acquir Immune Defic Syndr. 2004;35:367-375.

What is Serostim

Serostim® [somatropin (rDNA origin) for injection] is indicated for the treatment of HIV patients with wasting or cachexia to increase lean body mass and body weight, and improve physical endurance. Concomitant antiretroviral therapy is necessary.